Understand the Workup for AutoImmune Hepatitis
By John Joseph Pack MD
Published on 05/12/2026
Autoimmune Hepatitis is a chronic liver disease that may have an insidious or abrupt onset. Symptoms and signs include malaise, fatigue, rash, arthralgias, and jaundice. The incidence is higher in women. 25-50% of cases may be relatively asymptomatic and picked up on routine hepatic screening labs which may show only elevated aminotransferase levels. Alkaline phosphatase is often normal or near-normal. If suspected, follow up labs should be ordered including anti-nuclear antibody, anti-smooth muscle antibody, serum IgG levels, and liver-kidney microsomal antibody (LKM), all of which may be elevated. Treatment may include immunosuppressants such as corticosteroids and azathioprine.
Disclaimer: The content presented in grandroundsmd.com is provided for informational and educational purposes only. While efforts are made to ensure accuracy, grandroundsmd.com makes no representations or warranties regarding the completeness, reliability, or accuracy of the information contained in each article. The views and opinions expressed are those of the individual authors and do not necessarily reflect those of grandroundsmd.com. This publication is not intended to substitute for professional medical advice, diagnosis, or treatment. Readers are responsible for how they choose to use this information, and grandroundsmd.com assumes no responsibility or liability for any consequences arising from its application.
Discussion
Join the conversation! Login if you already have an account, or create an account. We would love to hear your perspective.
Comments
0Loading comments…
Your Next Read
